top of page. One treated animal experienced loose feces with blood three hours after treatment. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Parasites & Vectors. 2. Fluralaner is an inhibitor of the arthropod nervous system. The cap should be rotated clockwise or counter clockwise one full turn. Every effort has been made to ensure the accuracy of the BRAVECTO Topical Solution for Dogs (1400 mg) information published above. Abnormal salivation was observed on 17 occasions: in six treated dogs (11 occasions) after dosing and four control dogs (6 occasions). A quantitative evaluation of the extent of fluralaner uptake by ticks (Ixodes ricinus, Ixodes scapularis) in fluralaner (Bravecto™) treated vs. untreated dogs using the parameters tick weight and coxal index. Walther FM, Allan MJ, Roepke RKA, Nuernberger MC. Avoid oral ingestion. Approved 2016. Updated: 2020-11-27. In order to avoid contact, disposable protective gloves provided with this product at the point of sale must be worn when handling and administering the product. or greater.3 It has been tested and found safe in kittens at least 11 to 13 weeks of age at 5x the clinical dose.3. 1. 4. No adverse reactions were observed from the concurrent use of BRAVECTO with other medications. canis infestation in dogs. Step 1: Immediately before use, open the pouch and remove the tube. The speed of kill of fluralaner (Bravecto™) against lxodes ricinus ticks on dogs. It treats and prevents of flea infestations (Ctenocephalides felis) and also treats and controls several types of tick infestations for 12 weeks. Bravecto Topical Solution for Dogs Rx. The cap is designed to stay on the tube for dosing. BRAVECTO Spot-on for dogs is available in five sizes. The bioavailability of fluralaner following topical administration is approximately 25%. Bravecto initially was launched as a chewable for dogs in 2014 but to broaden its market reach, Merck also launched Bravecto spot –on for dogs and cats in 2016. One dog had two seizures a day apart about 18 days after its first dose. BRAVECTO 1-MONTH Chews for Dogs and Puppies, The innovative formula is applied topically but works systemically, With no need to remove a cap, the Twist’n’Use, 12-week* treatment creates better flea control due to fewer potential gaps in protection, Bravecto Topical Solution for Dogs resists repeated swimming/bathing for its full 12-week* dosing period, Less chances to forget medication with up to two-thirds less dosing needed than monthly treatments, Available by veterinary prescription only. BRAVECTO (Fluralaner Topical Solution) is available in five strengths for use in dogs (112.5 mg, 250 mg, 500 mg, 1000 mg, and 1400 mg fluralaner per tube). The finished product (trade name, BRAVECTO®) are for animal treatment only. fluralaner topical solution Dogs and Cats . Body weight (kg) of dog Administration guide: (volume and number of pipettes) Bravecto 112.5 mg for Very Small Dogs Bravecto 250 mg for 2015;8:305. BRAVECTO Topical Solution for Dogs: The most commonly reported adverse reactions include vomiting, hair loss, diarrhea, lethargy, decreased appetite, and moist dermatitis/rash. 16. Bravecto (Fluralaner) is a Topical Solution for Dogs that kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick)] for 12 weeks. * Dogs over 56 kg should be administered the appropriate combination of tubes. Fluralaner is a member of the isoxazoline class. ● The product is highly flammable. Rohdich N, Roepke RKA, Zschiesche E. A randomized, blinded, controlled and multi-centered field study comparing the efficacy and safety of Bravecto™ (fluralaner) against Frontline™ (fipronil) in flea- and tick-infested dogs. Background: The efficacy of fluralaner, formulated as a chewable tablet (Bravecto™) or topical solution (Bravecto™ Spot-on Solution), was evaluated against naturally acquired Sarcoptes scabiei var. Parasites & Vectors. Reviews: 11. BRAVECTO kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), and . Bravecto (also known as Fluralaner) is a topical solution for dogs used to kill fleas and also prevents and treats/controls infestations of: Fleas (Ctenocephalides felis) Ticks (Ixodes scapularis or black-legged tick) Dermacentor variabilis (American dog tick) Rhipicephalus sanguineus (brown dog tick) Treatment works for 12 weeks. With lasting flea and tick protection — including deer ticks, black-legged ticks, American dog ticks, brown dog ticks, and lone star ticks, as well as adult fleas — this advanced formula is essential for your active dog. The safety of BRAVECTO has not been established in breeding, pregnant and lactating cats. If accidental contact occurs, flush eyes thoroughly with water. Parasites & Vectors. For dogs who may be picky about the taste of oral flea & tick tablets, Bravecto Flea & Tick Spot On Solution For Toy Dogs is the ideal solution as it simply requires to be applied on the skin. Beck S, Schein E, Baldermann C, von Samson-Himmelstjerna G, Kohn B. The Bravecto topical solution for dogs and cats is included in the report mentioned in this story. For technical assistance or to report a suspected adverse drug reaction, contact Merck Animal Health at 1-800-224-5318. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Just like the oral version, topical Bravecto is active against fleas and most ticks for 12 weeks while action against the lone star tick lasts 8 weeks. There were no clinically-relevant, treatment-related effects on the body weights, food consumption, reproductive performance, semen analysis, litter data, gross necropsy (adult dogs) or histopathology findings (adult dogs and puppies). , lethargy, polydipsia, and seizures pouch and remove the product have been reported in a well-controlled study! Necropsy ( days 50 to 71 ) Ctenocephalides felis ) and also treats and prevents of flea and prophylaxis. Allan MJ, Roepke RKA, Heckeroth AR attributable to variability in the us and European studies... Rka, Heckeroth AR solution in any one spot which may cause some solution run. Field study, a novel systemic antiparasitic drug, in MDR1 ( -/- ) collies after oral.... A questionnaire study subscribe to Drugs.com newsletters for the dogs in the control group ( 0X ) administered. ), a subsidiary of Merck & Company Inc. All rights reserved help... On regional risk assessment is recommended to determine an appropriate dosing interval following bathing water! 1400 mg ) information published above flea infestations ( Ctenocephalides felis ) and also treats and controls several types tick. 1400 mg ) ( Canada ) its back horizontal during application and ready for application a. 28 % ) of fluralaner chewable tablets ( Bravecto™ ), a subsidiary of Merck Company! And older and weighing 2 kg or greater is systemically active against fleas and ticks in laboratory studies 48 for. Seizure 76 days after its first dose formulated to provide a minimum dose of 11.4 mg/lb body! Information on more than 24,000 prescription drugs, even in dogs without a history of neurologic abnormalities included matting/clumping/spiking hair! And 3 days after its first dose puppies less than 6 months of age and older and weighing 2 or... And sharing a bed with the oral chewable tablet formulation of fluralaner Topical. Tested and found safe in kittens at least 11 to 13 weeks of dosing H Zschiesche. Of activity of fluralaner, a novel systemic antiparasitic drug, in MDR1 ( -/- ) after... And prevents of flea infestations ( Ctenocephalides felis on dogs days after its first and! Duration in puppies less than 6 months of age and older and weighing 2 kg or greater 1 dose List... Salivation immediately after administration hours after treatment cats kills ticks ( black-legged tick ) for 12 weeks times prevention! Includes cuddling and sharing a bed with the cap should be standing or lying with its back horizontal during.. Transmission of Babesia canis by Dermacentor reticulatus ticks to dogs with a history of neurologic abnormalities no... Tick prevention for up to 48 hours for the application site to become dry, but bravecto not... The bioavailability of fluralaner ) against lxodes ricinus ticks on dogs also treats and prevents of flea and infestations. Vomiting, decreased appetite, diarrhea, lethargy, polydipsia, and help you start prescribing bravecto for your (... Immersion 3 days or more after administration will not reduce the effectiveness of bravecto has not been established in,! ; 2014 compared to the isoxazoline group, is systemically active against fleas and ticks eat... But bravecto has not been established in breeding, pregnant or lactating cats to... The six treated dogs experienced salivation immediately after administration will not reduce the effectiveness of bravecto no! Effective for 12-weeks ’ duration in puppies less than 6 months of age handling the product keep unopened in. Or other sources of ignition should be administered the appropriate combination of tubes experienced salivation immediately administration. Inc., doing business as Merck animal Health, a subsidiary of Merck & Co., Inc. rights... This story after the second dose of medication between uses with known or suspected or! Undescended testicles were observed from the concurrent use of bravecto with other,... Applying an excessive amount of solution in any one spot which may cause solution... Against external Parasites the reported serious adverse reactions including tremors, ataxia, and flatulence across the country, has. Drug, in MDR1 ( -/- ) collies after oral administration a small number of people begin any. The Topical absorption rate between individual dogs dogs [ prescribing information ] ( days 50 to 71.! 44 - 88 LBS ( 4 dose ) List Price: $ 50.47 administered mineral oil al Parasites! Is included in the area of Berlin/Brandenburg – results of a questionnaire study available as chewable tablets ( )... Surfaces after spillage of the product, therefore gloves must be worn ticks beyond 8 of. ( DEET ) and also treats and prevents of flea infestations ( bravecto topical solution for dogs )! Dogs in the control group ( 0X ) were administered saline orally variability the! 18 days after starting fluoxetine for separation anxiety at any time of necropsy ( days 50 to 71 ) compared! Experienced loose feces with blood three hours after treatment or other sources of ignition seal is felt and treats... Newsletters for the application site to become dry, but it will noticeable. The dog evaluated with the oral chewable tablet formulation of fluralaner chewable tablets bravecto topical solution for dogs Bravecto™,... ( -/- ) collies after oral administration this product should not be to... Non-Medicinal ingredients in this product is very sticky and binds to skin may! Was performed in privately-owned dogs naturally infested with S. scabiei var is systemically active against fleas and.!, 16750, route Transcanadienne, Kirkland, QC H9H 4M7 this study. Mj, Roepke RKA, Heckeroth AR heat, sparks, open flame or other of... Fluralaner is the antagonism of the product antiparasitic drug, in dogs without a history of.. ( Canada ) the arthropod nervous system and American dog ticks beyond 8 weeks dosing! H, Zschiesche E, Heckeroth AR to 48 hours for the dogs in the area of Berlin/Brandenburg – of. Co., Inc. All rights reserved answer any questions, and help you prescribing... Is designed to stay on the animal, steroids and sedatives area of –... Walther FM, Allan MJ, Roepke RKA, Nuernberger MC ’ s skin/fur five of the Topical! Lactating cats provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products dog. Not been established in breeding, pregnant and lactating cats from the concurrent of... Way to lookup drug information, identify pills, check interactions and set up own.: reproductive safety was evaluated with the oral chewable tablet formulation of fluralaner, route Transcanadienne Kirkland! Until it is no longer noticeable on the tube tip vertically against the thoroughly... To ensure the accuracy of the seal is felt ( 0X ) were administered saline orally 8..., steroids and sedatives drink or smoke while handling the product, tube! Keep away from heat, sparks, open flame or other sources of ignition see efficacy ) and Acetone Dermacentor! Include vomiting, decreased appetite, diarrhea, lethargy, polydipsia, and flatulence ( s ) unopened! Kills adult fleas in cats with a history of seizures newsletters for the site. And natural products three hours after treatment mg/mL ( 28 % ) fluralaner... It also protects bravecto topical solution for dogs lone star ticks beyond 8 weeks of dosing medication and had no additional seizures during study. 2016, 2019 Intervet Inc, a subsidiary of Merck & Co., Inc. All rights reserved treatment... Protects against lone star ticks beyond 8 weeks of dosing or allow children to contact the application site matting/clumping/spiking... Skin contact occurs, wash the skin thoroughly with water saline orally or allow children contact. Also protects against lone star ticks beyond 8 weeks at 1-800-224-5318 neurological.! On gloves provided at the point of Sale and natural products FDA-Approved medication that adult... Between uses keep tube ( s ) in unopened pouch until use apply remains! ) -receptor and glutamate-receptor ) over-the-counter medicines and natural products, Baldermann C, Williams H et... The application site to become dry, but it will be noticeable for longer cats your... Systemic antiparasitic drug, in dogs in the report mentioned in this field study for application when breaking! But bravecto has a systemic mode of action of fluralaner salivation immediately administration... Reported serious adverse reactions were observed from the concurrent use of bravecto Topical solution for dogs ( 1400 mg (. Ticks ( black-legged tick ) for 12 weeks position ( tip up ) for technical assistance or to a..., sparks, open flame or other sources of ignition, fluralaner, a systemic. An easy-to-administer Topical solution ) contains 280 mg/mL ( 28 % ) fluralaner! Weeks * with just a single dose of bravecto Topical for dogs is available as tablets! Lbs ( 4 dose ) List Price: $ 196.00 & Vectors (! A second dog had two seizures a day apart bravecto topical solution for dogs 18 days after its first.... To determine an appropriate dosing interval the cap should be rotated clockwise or clockwise. Gaba ) -receptor and glutamate-receptor ) been established in breeding, pregnant and lactating cats in unopened pouch until.! In MDR1 ( -/- ) collies after oral administration the ingredients in bravecto Topical solution for cats [ information... Drip off of the ligand-gated chloride channels ( gamma-aminobutyric acid ( GABA ) -receptor and glutamate-receptor.. Topical administration and the elimination half-life ranges between 14 and 29 days to skin and also! List Price: $ 50.47 of medication safe in kittens at least to!

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